Mainz 05 vs RB Leipzig: prediction & betting odds 13 September 2025

The Matchday 3 Bundesliga clash between Mainz and Leipzig will take place on September 13 at the Mewa Arena. Mainz vs. Leipzig: prediction and betting odds, statistics.

Mainz

In the last round, Bo Henriksen's side drew 1-1 away to Wolfsburg. As a result, Mainz has failed to win 10 of their last 11 Bundesliga matches (6 draws, 4 losses). Moreover, they have not kept a clean sheet in their last 13 league matches. The team has earned one point and is currently in 13th place in the standings.


  • The team has not lost in 13 of their last 14 home matches in the Bundesliga (6 wins, 7 draws).
  • Both teams have scored in 5 of Mainz's last 6 home league matches.
  • Mainz has scored exactly 1 or 2 goals in 10 of their last 12 home Bundesliga games.

Predicted lineup for Mainz (3-4-3)

Robin Zentner – Danny da Costa, Stefan Bell, Dominik Kohr – Anthony Caci, Nadiem Amiri, Kaishu Sano, Philipp Mwene – Arno Norden, Nelson Weiper, Lee Jae-sung.


Forward Benedict Hollerbach will miss the match due to injury. Midfielder Paul Nebel is suspended.

Leipzig

Ole Werner's side defeated Hoffenheim 2-0 at home in the previous round. As a result, Leipzig ended their six-match winless streak in the Bundesliga (3 draws, 3 losses). Furthermore, it was only the second time in their last ten league matches that they kept a clean sheet. In the standings, the club has three points and is in 11th place. Notably, Leipzig has conceded six goals this Bundesliga season, only ahead of two teams in this regard.


  • The team has not won 10 of their last 11 away Bundesliga matches (5 draws, 5 losses).
  • Leipzig has failed to score in 7 of their last 8 away league matches.
  • At least four goals have been scored in 6 of Leipzig's last 9 Bundesliga matches.

Predicted lineup for Leipzig (4-3-3)

Peter Gulacsi – David Raum, Castello Lukeba, Willi Orban, Bote Baku – Antonio Nusa, Christoph Baumgartner, Xaver Schlager – Ezekiel Banzuzi, Romulo Cardoso, Johan Bakayoko.


Forward Ezekiel Banzuzi will miss the game due to injury.

Referee

Sven Jablonski (Germany)


Matches – 16 (Bundesliga, 2024/25–2025/26);

Yellow cards shown (including second yellows) – 63;

Average yellow cards per match – 3.9;

Red cards shown – 3;

Average fouls per match – 20;

Penalties – 19%.

Match Prediction: Mainz vs. Leipzig

The hosts have not had the best start to the current championship, but Mainz is capable of making progress at home. They have lost just once in their last 14 home Bundesliga matches, winning six times in that span. Notably, their victories include matches against Bayern Munich (2-1) and Borussia Dortmund (3-1). Additionally, they managed to draw against Bayer Leverkusen (2-2) and Eintracht Frankfurt (1-1) during this period.


Leipzig often struggles away from home, having won only once in their last 11 away league matches (5 draws, 5 losses). Moreover, they failed to score in seven of these matches. Considering that Ole Werner's side suffered a heavy defeat to Bayern Munich (0-6) in their first away match of the current Bundesliga season, I expect a strong performance from the hosts. My prediction: Mainz with a handicap (0)


* For each team, the starting lineup from their previous match in this tournament is indicated.

Mainz 05 — RB Leipzig betting tips 13 September 2025

Mainz 05 have started the season slowly, taking only one point from two matchdays, yet they have reached the UEFA Europa Conference League group stage. That means the squad faces fixture congestion, so rotation and workload management will be key. RB Leipzig, by contrast, have no European football and can focus entirely on the Bundesliga.

Mainz 05 have not impressed with results so far: a last-minute defeat to Köln (0:1) and a draw with VfL Wolfsburg (1:1) have left the club towards the bottom of the standings. However, the team is not without threat — across two matchdays they generated 3.5 xG but scored only once. The hosts have already made their mark in Europe and reached the UEFA Europa Conference League group stage by beating Rosenborg BK in qualifying (1:2, 4:1). Mainz also have an excellent recent head-to-head record against RB Leipzig, with only one defeat in the last six meetings.

RB Leipzig opened with a heavy defeat in Munich (0:6), but they responded with a home win over Heidenheim (2:0), in which they produced 2.22 xG. After the departures of Xavi Simons, Benjamin Šeško and Loïs Openda, the attack has weakened. The replacements are Yan Diomande, Rômulo Cardoso и Conrad Harder, but these are players of lesser calibre, all signed with the future in mind. Away matches have been a problem for some time, with only one win in their last 11 Bundesliga away fixtures.

At home, Mainz 05 will deny space in dangerous areas and close the gaps between the lines, while RB Leipzig are still adjusting after losing key players. The hosts have not looked that forlorn at the start and they are capable of taking points off the visitors, who have been weakened by the departure of their stars.

Betting prediction
Mainz 05 to win or draw
Cf
Odds
53/100
Bet now

Mainz 05 vs RB Leipzig Odds

Current season

Logo Mainz 05 Logo RB Leipzig
0 Wins 1
1 Lost 1
1 Draws 0
0.5 GF per game 1
1 GA per game 3
9 Corners per game 4.5
2.5 Yellow cards per game 1.5

Bundesliga: previous matches in the tournament

Mainz 05
31.08.25
Wolfsburg
Mainz 05
D
24.08.25
Mainz 05
Köln
L
More matches
RB Leipzig
30.08.25
RB Leipzig
Heidenheim
W
22.08.25
Bayern Munich
RB Leipzig
L
More matches

H2H: Mainz 05 — RB Leipzig

Bundesliga 2024-2025
01.03.25
RB Leipzig
Mainz 05
19.10.24
Mainz 05
RB Leipzig
Bundesliga 2023-2024
30.03.24
RB Leipzig
Mainz 05
04.11.23
Mainz 05
RB Leipzig
Bundesliga 2022-2023
01.04.23
RB Leipzig
Mainz 05
08.10.22
Mainz 05
RB Leipzig
Bundesliga 2021-2022
08.01.22
RB Leipzig
Mainz 05
15.08.21
Mainz 05
RB Leipzig
Bundesliga 2020-2021
23.01.21
Mainz 05
RB Leipzig
20.09.20
RB Leipzig
Mainz 05
Bundesliga 2019-2020
24.05.20
Mainz 05
RB Leipzig
02.11.19
RB Leipzig
Mainz 05
Bundesliga 2018-2019
03.05.19
Mainz 05
RB Leipzig
16.12.18
RB Leipzig
Mainz 05
Bundesliga 2017-2018
29.04.18
Mainz 05
RB Leipzig
09.12.17
RB Leipzig
Mainz 05
Bundesliga 2016-2017
05.04.17
Mainz 05
RB Leipzig
06.11.16
RB Leipzig
Mainz 05
More matches

Tables

Team Played W D L Goals Points Form
1
Bayern Munich
2 2 0 0 9:2 6
2
Eintracht Frankfurt
2 2 0 0 7:2 6
3
Köln
2 2 0 0 5:1 6
4
Borussia Dortmund
2 1 1 0 6:3 4
5
St. Pauli
2 1 1 0 5:3 4
6
Wolfsburg
2 1 1 0 4:2 4
7
Augsburg
2 1 0 1 5:4 3
8
Stuttgart
2 1 0 1 2:2 3
9
Hoffenheim
2 1 0 1 3:4 3
10
Union Berlin
2 1 0 1 2:4 3
11
RB Leipzig
2 1 0 1 2:6 3
12
Bayer 04
2 0 1 1 4:5 1
13
Mainz 05
2 0 1 1 1:2 1
14
Borussia Mönchengladbach
2 0 1 1 0:1 1
15
Hamburger
2 0 1 1 0:2 1
16
Werder Bremen
2 0 1 1 4:7 1
17
Heidenheim
2 0 0 2 1:5 0
18
Freiburg
2 0 0 2 2:7 0
Team Played W D L Goals Points Form
1
Bayern Munich
1 1 0 0 6:0 3
2
Eintracht Frankfurt
1 1 0 0 4:1 3
3
Köln
1 1 0 0 4:1 3
4
Borussia Dortmund
1 1 0 0 3:0 3
5
RB Leipzig
1 1 0 0 2:0 3
6
Union Berlin
1 1 0 0 2:1 3
7
Stuttgart
1 1 0 0 1:0 3
8
St. Pauli
1 0 1 0 3:3 1
9
Werder Bremen
1 0 1 0 3:3 1
10
Wolfsburg
1 0 1 0 1:1 1
11
Borussia Mönchengladbach
1 0 1 0 0:0 1
12
Augsburg
1 0 0 1 2:3 0
13
Bayer 04
1 0 0 1 1:2 0
14
Mainz 05
1 0 0 1 0:1 0
15
Hoffenheim
1 0 0 1 1:3 0
16
Heidenheim
1 0 0 1 1:3 0
17
Freiburg
1 0 0 1 1:3 0
18
Hamburger
1 0 0 1 0:2 0
Team Played W D L Goals Points Form
1
Eintracht Frankfurt
1 1 0 0 3:1 3
2
Wolfsburg
1 1 0 0 3:1 3
3
Augsburg
1 1 0 0 3:1 3
4
St. Pauli
1 1 0 0 2:0 3
5
Bayern Munich
1 1 0 0 3:2 3
6
Hoffenheim
1 1 0 0 2:1 3
7
Köln
1 1 0 0 1:0 3
8
Borussia Dortmund
1 0 1 0 3:3 1
9
Bayer 04
1 0 1 0 3:3 1
10
Mainz 05
1 0 1 0 1:1 1
11
Hamburger
1 0 1 0 0:0 1
12
Stuttgart
1 0 0 1 1:2 0
13
Borussia Mönchengladbach
1 0 0 1 0:1 0
14
Heidenheim
1 0 0 1 0:2 0
15
Werder Bremen
1 0 0 1 1:4 0
16
Freiburg
1 0 0 1 1:4 0
17
Union Berlin
1 0 0 1 0:3 0
18
RB Leipzig
1 0 0 1 0:6 0

Team lineups

The line-ups will be known a few hours before kick-off
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